Non-invasive biomarkers to diagnose infant urinary tract obstruction

One in every 500 babies is born with a condition called ureteropelvic junction obstruction (UPJO), an obstruction of the ureter that prevents urine from flowing from one or both of the kidneys into the bladder. Usually diagnosed prenatally, UPJO can cause urinary tract infections and poor growth for infants; it can also result in chronic kidney disease and an increased risk for cardiovascular disease in later life.